Compile Data Set for Download or QSAR
maximum 50k data
Found 866 of ic50 data for polymerid = 50001234,50001393,50002702
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029174(CHEMBL131973 | N-(1-methylethyl)-3-[(3-prop-2-en-1...)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038093((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0400nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038102((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0400nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029177(CHEMBL134337 | Propionic acid 3-allyl-4-(3-isoprop...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038087((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0600nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038138((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0700nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038092((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.0900nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038089((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.120nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038120((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.130nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038123((6R,7R)-4,7-Dihydroxy-1-(5-methyl-6-phenyl-hexyl)-...)
Affinity DataIC50:  0.140nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038122((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.160nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038121((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.170nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038091((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.190nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038151((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.190nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038125((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.200nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038090((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.200nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292336(CHEMBL507677 | desacetoxy-zaragozic acid)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292415(CHEMBL504845 | Zaragozic Acid B)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029166(Acetaldehyde O-[3-allyl-4-(3-isopropylamino-propox...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038119((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.210nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.230nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.240nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038103((6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy...)
Affinity DataIC50:  0.240nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038114((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.260nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038102((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.280nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038135((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.280nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.290nMAssay Description:In vitro inhibitory activity against rat squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038089((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.300nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(CHEMBL505374 | zaragozic acid C)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442114(CHEMBL2441090)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038127((6R,7R)-1-(4-Acetoxy-5-methyl-6-phenyl-hexyl)-4,7-...)
Affinity DataIC50:  0.370nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038128((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.380nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292333(CHEMBL505374 | zaragozic acid C)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038104((6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy...)
Affinity DataIC50:  0.420nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50338903(CHEMBL1684849 | Ethyl 1-{4-[{4-chloro-2-[(2-fluoro...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50388376(CHEMBL2057637)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of squalene synthase in rat hepatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038101((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.520nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285068((S)-2-{[(1S,2S)-3-(3,4-Dichloro-phenyl)-2-(2-fluor...)
Affinity DataIC50:  0.520nMAssay Description:Inhibitory activity of the compound against squalene synthase (SQS) obtained from HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285068((S)-2-{[(1S,2S)-3-(3,4-Dichloro-phenyl)-2-(2-fluor...)
Affinity DataIC50:  0.520nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50388375(CHEMBL2057636)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of squalene synthase in rat hepatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029171(CHEMBL341371 | N-[3-Benzyl-4-(3-isopropylamino-pro...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029159(CHEMBL132881 | [3-(2-Allyl-4-butoxy-phenoxy)-propy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of rat microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038093((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.640nMAssay Description:compound required to inhibit 50% activity of yeast squalene synthase enzyme (YESS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50038088((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  0.660nMAssay Description:Tested for inhibition against squalene synthase enzyme in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50388378(CHEMBL2057639)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of squalene synthase in rat hepatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50388348(CHEMBL2057952)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of squalene synthase in rat hepatic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50:  0.700nMAssay Description:Inhibitory activity against rat liver microsomal squalene synthase was determined using [3H]-FPP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442115(CHEMBL2440128)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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